15O positron emission tomographic scanning in predominantly never-treated acute schizophrenic patients.
Details
Serval ID
serval:BIB_F612F8B8F9FE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
15O positron emission tomographic scanning in predominantly never-treated acute schizophrenic patients.
Journal
Lancet
ISSN
0140-6736 (Print)
ISSN-L
0140-6736
Publication state
Published
Issued date
1983
Volume
2
Number
8365-66
Pages
1448-1452
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Abstract
Positron emission tomography with oxygen-15 was used to compare regional cerebral blood flow and the regional cerebral metabolic rate of oxygen in a group of predominantly never-treated, acute schizophrenic patients and in matched controls. The results of this study did not support the hypothesis that schizophrenics have reduced frontal blood flow and/or metabolism; and only equivocal support was obtained for the hypothesis that metabolism within the basal ganglia is reduced in schizophrenics. However, support was obtained for the hypothesis that an abnormality in hemisphere laterality may underlie schizophrenic illness.
Keywords
Acute Disease, Basal Ganglia/metabolism, Brain/radionuclide imaging, Cerebrovascular Circulation, Female, Functional Laterality, Humans, Male, Oxygen/metabolism, Oxygen Radioisotopes/diagnostic use, Regional Blood Flow, Schizophrenia/physiopathology, Tomography, Emission-Computed/methods
Pubmed
Web of science
Create date
09/10/2011 18:41
Last modification date
20/08/2019 17:22
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