Influence of the implanted pulse generator as reference electrode in finite element model of monopolar deep brain stimulation.

Détails

ID Serval
serval:BIB_F2C694F3E417
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Influence of the implanted pulse generator as reference electrode in finite element model of monopolar deep brain stimulation.
Périodique
Journal of Neuroscience Methods
Auteur(s)
Walckiers Gregoire, Fuchs Benjamin, Thiran Jean-Philippe, Mosig Juan R., Pollo Claudio
ISSN
1872-678X[electronic], 0165-0270[linking]
Statut éditorial
Publié
Date de publication
2010
Volume
186
Numéro
1
Pages
90-96
Langue
anglais
Résumé
Electrical deep brain stimulation (DBS) is an efficient method to treat movement disorders. Many models of DBS, based mostly on finite elements, have recently been proposed to better understand the interaction between the electrical stimulation and the brain tissues. In monopolar DBS, clinically widely used, the implanted pulse generator (IPG) is used as reference electrode (RE). In this paper, the influence of the RE model of monopolar DBS is investigated. For that purpose, a finite element model of the full electric loop including the head, the neck and the superior chest is used. Head, neck and superior chest are made of simple structures such as parallelepipeds and cylinders. The tissues surrounding the electrode are accurately modelled from data provided by the diffusion tensor magnetic resonance imaging (DT-MRI). Three different configurations of RE are compared with a commonly used model of reduced size. The electrical impedance seen by the DBS system and the potential distribution are computed for each model. Moreover, axons are modelled to compute the area of tissue activated by stimulation. Results show that these indicators are influenced by the surface and position of the RE. The use of a RE model corresponding to the implanted device rather than the usually simplified model leads to an increase of the system impedance (+48%) and a reduction of the area of activated tissue (-15%).
Mots-clé
Deep Brain Stimulation, Finite Element, Volume Of Tissue Activated, Diffusion Tensor, Parkinson's Disease, Subthalamic Nucleus, Parkinsons-Disease, Follow-Up, Tissue, Head, Activation, Volume, Field
Pubmed
Web of science
Création de la notice
09/03/2010 14:24
Dernière modification de la notice
20/08/2019 17:19
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