Enterocystoplasty using modified pedicled, detubularized, de-epithelialized sigmoid patches in the mini-pig model.

Details

Serval ID
serval:BIB_F229BB13374B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Enterocystoplasty using modified pedicled, detubularized, de-epithelialized sigmoid patches in the mini-pig model.
Journal
Journal of Urology
Author(s)
Lutz N., Frey P.
ISSN
0022-5347 (Print)
ISSN-L
0022-5347
Publication state
Published
Issued date
08/1995
Peer-reviewed
Oui
Volume
154
Number
2 Pt 2
Pages
893-898
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Enterocystoplasty and gastrocystoplasty have been developed to restore adequate bladder capacity but they still result in the undesired harmful contact of urine with the intestinal mucosa. In an attempt to prevent this nonphysiological interface we performed several modified enterocystoplasties in the mini-pig model using a pedicled, detubularized, de-epithelialized sigmoid patch. Five techniques of patch coverage were used to evaluate urothelial growth or survival on the sigmoid patch. All but 1 patch had intestinal mucosa remnants with mucocele formation. When no coverage was applied or a biodegradable polyglactin mesh was temporarily covering the pedicled, detubularized, de-epithelialized sigmoid patch, severe shrinkage occurred. Partial cover with autologous urothelium islets seemed to decrease shrinkage. Adequate urothelium survival and satisfactory elastic properties of the patch were observed when total cover of the sigmoid patch was achieved with a sheet of homologous urothelium recovering autologous urothelial islets or when the patch was applied to protruding urothelium obtained following sagittal posterior detrusor myotomy.
Keywords
Animals, Colon, Sigmoid/transplantation, Female, Intestinal Mucosa/pathology, Swine, Swine, Miniature, Transplantation/methods, Urinary Bladder/surgery
Pubmed
Web of science
Create date
28/02/2008 10:25
Last modification date
20/08/2019 16:19
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