Digitoxin metabolism by rat liver microsomes.

Détails

Ressource 1Télécharger: BIB_EE7D4CC5FB04.P001.pdf (556.51 [Ko])
Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_EE7D4CC5FB04
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Digitoxin metabolism by rat liver microsomes.
Périodique
Biochemical pharmacology
Auteur(s)
Schmoldt A., Benthe H.F., Haberland G.
ISSN
1873-2968 (Electronic)
ISSN-L
0006-2952
Statut éditorial
Publié
Date de publication
01/09/1975
Peer-reviewed
Oui
Volume
24
Numéro
17
Pages
1639-1641
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Background: Malnutrition among hospitalized patients increases length of stay (LOS) and carries extra hospitalization costs.
Objective: To review the impact of malnutrition on hospital LOS and costs in Europe.
Methods: PubMed and Google Scholar search. All articles from January 2004 until November 2014 were identified. Reference lists of relevant articles were also manually searched.
Results: Ten studies on LOS and nine studies on costs were reviewed. The methods used to assess
malnutrition and to calculate costs differed considerably between studies. Malnutrition led to an
increased LOS ranging from 2.4 to 7.2 days. Among hospitalized patients, malnutrition led to an additional individual cost ranging between 1640 V and 5829 V. At the national level, the costs of malnutrition ranged between 32.8 million V and 1.2 billion V. Expressed as percentage of national health expenditures, the values ranged between 2.1% and 10%.
Conclusions: In Europe, malnutrition leads to an increase in LOS and in hospital costs, both at the individual and the national level. Standardization of methods and results reported is needed to adequately
compare results between countries.
© 2015 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights
reserved.
Mots-clé
Animals, Chromatography, Thin Layer, Digitoxigenin/metabolism, Digitoxin/metabolism, Hydroxylation, In Vitro Techniques, Male, Microsomes, Liver/metabolism, NADP/metabolism, Rats, Time Factors
Open Access
Oui
Création de la notice
10/02/2016 16:07
Dernière modification de la notice
11/02/2020 7:19
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