Late onset Leber's optic neuropathy: a case confused with ischaemic optic neuropathy

Détails

ID Serval
serval:BIB_E4A7F2C6AC9A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Late onset Leber's optic neuropathy: a case confused with ischaemic optic neuropathy
Périodique
British Journal of Ophthalmology
Auteur(s)
Borruat  F. X., Green  W. T., Graham  E. M., Sweeney  M. G., Morgan-Hughes  J. A., Sanders  M. D.
ISSN
0007-1161 (Print)
Statut éditorial
Publié
Date de publication
09/1992
Volume
76
Numéro
9
Pages
571-3
Notes
Case Reports
Journal Article --- Old month value: Sep
Résumé
A case is reported of a 63-year-old man with progressive central visual loss in one eye followed 11 months later by involvement of the fellow eye. A diagnosis of chronic ischaemic optic neuropathy was considered. However, despite a negative family history, the absence of electrocardiographic abnormalities, and minimal fundus changes a diagnosis of Leber's optic neuropathy was made on the basis of magnetic resonance imaging findings and the mitochondrial DNA mutation at base pair 11778.
Mots-clé
DNA, Mitochondrial/analysis Diagnosis, Differential Fluorescein Angiography Humans Magnetic Resonance Imaging Male Middle Aged Optic Atrophies, Hereditary/*diagnosis/genetics Optic Atrophy/diagnosis Optic Nerve/pathology
Pubmed
Web of science
Open Access
Oui
Création de la notice
28/01/2008 12:38
Dernière modification de la notice
20/08/2019 16:08
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