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Article: article from journal or magazin.
The diagnosis of chronic inflammatory demyelinating polyneuropathy: a Delphi-method approach.
Journal of Neurology
French CIDP study group
Antoine JC., Arne Bes MC. , Attarian S., Bouche P., Bouhour F., Camdessanche JP., Careyron A., Créange A., De Sèze J., Delmont E., Echaniz Laguna YA. , Franques J., Gallard J., Guéguen A., Kuntzer T., Lacour A., Lagrange E., Lefaucheur JP., Léger JM., Lozeron P., Magot A., Magy L., Maisonobe T., Malapert D., Nicolas G., Ochsner F., Pouget J., Schmidt E., Taithe F., Vallat JM., Vial C., Viala K., Adams D.
Publication types: Journal ArticlePublication Status: ppublish. T. Kuntzer fait partie de French CIDP study group
The diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) is based on a set of clinical and neurophysiological parameters. However, in clinical practice, CIDP remains difficult to diagnose in atypical cases. In the present study, 32 experts from 22 centers (the French CIDP study group) were asked individually to score four typical, and seven atypical, CIDP observations (TOs and AOs, respectively) reported by other physicians, according to the Delphi method. The diagnoses of CIDP were confirmed by the group in 96.9 % of the TO and 60.1 % of the AO (p < 0.0001). There was a positive correlation between the consensus of CIDP diagnosis and the demyelinating features (r = 0.82, p < 0.004). The European CIDP classification was used in 28.3 % of the TOs and 18.2 % of the AOs (p < 0.002). The French CIDP study group diagnostic strategy was used in 90 % of the TOs and 61 % of the AOs (p < 0.0001). In 3 % of the TOs and 21.6 % of the AOs, the experts had difficulty determining a final diagnosis due to a lack of information. This study shows that a set of criteria and a diagnostic strategy are not sufficient to reach a consensus for the diagnosis of atypical CIDP in clinical practice.
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