Mecanisme d'action de l'aldosterone dans la vessie de crapaud: correlation entre reponse biologique et occupation des sites recepteurs. [Mechanism of action of aldosterone on the toad bladder: correlation between biological response and occupation of the receptor sites]

Details

Serval ID
serval:BIB_E301FDEB958B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Mecanisme d'action de l'aldosterone dans la vessie de crapaud: correlation entre reponse biologique et occupation des sites recepteurs. [Mechanism of action of aldosterone on the toad bladder: correlation between biological response and occupation of the receptor sites]
Journal
Nephrologie
Author(s)
Claire  M., Rossier  B. C.
ISSN
0250-4960
Publication state
Published
Issued date
1985
Peer-reviewed
Oui
Volume
6
Number
3
Pages
113-7
Notes
English Abstract
In Vitro
Journal Article
Abstract
The mechanism of aldosterone uptake in the epithelial cells of toad bladder was studied using mathematical modeling. It seems that two types of receptors are necessary to obtain a complete action of aldosterone. If this observation is confirmed, the traditional notion of type I receptors i.e. mineralocorticoids receptors and type II receptors i.e. glucocorticoids receptors has to be reviewed.
Keywords
Aldosterone/metabolism/*pharmacology Animals Bufo marinus Mathematics Models, Biological Receptors, Glucocorticoid/metabolism Receptors, Mineralocorticoid Receptors, Steroid/*metabolism Urinary Bladder/*drug effects
Pubmed
Web of science
Create date
24/01/2008 13:01
Last modification date
20/08/2019 16:06
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