Acute myocardial infarction in women: influence of gender on mortality and prognostic variables
Details
Serval ID
serval:BIB_E217EFD69A6A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Acute myocardial infarction in women: influence of gender on mortality and prognostic variables
Journal
American Journal of Cardiology
ISSN
0002-9149 (Print)
Publication state
Published
Issued date
07/1988
Volume
62
Number
1
Pages
1-7
Notes
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jul 1
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jul 1
Abstract
The contention that mortality after acute myocardial infarction (AMI) is increased in women compared with men has been controversial, with findings in a recent multicenter study suggesting that gender plays an important prognostic role. To assess whether or not early and late mortality after AMI is greater in women, 2,089 patients (1,551 men, 538 women) were followed for 1 year after AMI. In the hospital, women had an increased mortality compared to men (17.5 vs 12.3%, p less than 0.003) and were on average 7 years older, whereas after hospital discharge and up to 1 year no difference in mortality was observed. Multivariate analyses of historical, clinical and laboratory features demonstrated that gender had no independent predictive value when variables that included age, congestive heart failure in the hospital, history of congestive failure, prior AMI and diabetes mellitus were considered. Moreover, when age stratification was performed, the significant difference of in-hospital mortality between genders was no longer present. Causes of death in the hospital and during 1 year after hospital discharge were similar between men and women, whether or not age stratification was performed. Several baseline clinical characteristics were different between men and women; a history of systemic hypertension and congestive heart failure occurred more frequently in women and previous AMI and smoking occurred more commonly in men. Also, the value of several other important prognostic indicators after AMI, such as the ejection fraction, was found to differ between men and women.(ABSTRACT TRUNCATED AT 250 WORDS)
Keywords
Aged
Diabetes Complications
Female
Heart Diseases/mortality
Heart Failure, Congestive/complications
Humans
Male
Middle Aged
Myocardial Infarction/complications/*mortality/physiopathology
Prognosis
Risk Factors
Sex Factors
Stroke Volume
Pubmed
Web of science
Create date
25/01/2008 15:00
Last modification date
20/08/2019 17:06