Article: article from journal or magazin.
Gray matter decrease in patients with chronic tension type headache.
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
Using MRI and voxel-based morphometry, the authors investigated 20 patients with chronic tension type headache (CTTH) and 20 patients with medication-overuse headache and compared them to 40 controls with no headache history. Only patients with CTTH demonstrated a significant gray matter decrease in regions known to be involved in pain processing. The finding implies that the alterations are specific to CTTH rather than a response to chronic head pain or chronification per se.
Adolescent, Adult, Age Factors, Age of Onset, Aged, Anti-Inflammatory Agents, Non-Steroidal/adverse effects, Atrophy/diagnosis, Atrophy/etiology, Brain/pathology, Brain/physiopathology, Brain Mapping, Female, Functional Laterality/physiology, Headache Disorders, Secondary/chemically induced, Headache Disorders, Secondary/diagnosis, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Predictive Value of Tests, Tension-Type Headache/diagnosis, Tension-Type Headache/physiopathology, Tryptamines/adverse effects
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