Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists.

Chowers, Y.; Sturm, A.; Sans, M.; Papadakis, K.; Gazouli, M.; Harbord, M.; Jahnel, J.; Mantzaris, G.J.; Meier, J.; Mottet, C.; Peyrin-Biroulet, L.; Allez, M.

doi:10.1016/j.crohns.2010.05.011

Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists.

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Serval ID

serval:BIB_D2408C003E03

Type

Article: article from journal or magazin.

Publication sub-type

Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.

Collection

Publications

Institution

UNIL/CHUV

Title

Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists.

Journal

Journal of Crohn's and Colitis

Author(s)

Chowers Y., Sturm A., Sans M., Papadakis K., Gazouli M., Harbord M., Jahnel J., Mantzaris G.J., Meier J., Mottet C., Peyrin-Biroulet L., Allez M.

ISSN

1876-4479[electronic], 1873-9946[linking]

Publication state

Published

Issued date

2010

Volume

Number

Pages

367-376

Language

english

Notes

Publication types: Journal Article
Publication Status: ppublish

Abstract

This second section of the first ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases addresses the biological roles of TNFα and the effects and mechanisms of action of TNFα antagonists. Mechanisms underlying their failure, including induction of TNF-independent inflammatory pathways and phenomena of paradoxical inflammation are discussed.

OAI-PMH

oai:serval.unil.ch:BIB_D2408C003E03

DOI

10.1016/j.crohns.2010.05.011

Pubmed

21122531

Web of science

000284137700002

Open Access

Yes

Create date

25/02/2011 15:50