Nutrigenomics and nutrigenetics.

Détails

ID Serval
serval:BIB_D14BB5D421A8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Nutrigenomics and nutrigenetics.
Périodique
Current Opinion In Lipidology
Auteur(s)
Ordovas J.M., Mooser V.
ISSN
0957-9672 (Print)
ISSN-L
0957-9672
Statut éditorial
Publié
Date de publication
2004
Volume
15
Numéro
2
Pages
101-108
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S. ; Review
Résumé
PURPOSE OF REVIEW: Nutritional genomics has tremendous potential to change the future of dietary guidelines and personal recommendations. Nutritional genomics covers nutrigenomics, which explores the effects of nutrients on the genome, proteome and metabolome, and nutrigenetics, the major goal of which is to elucidate the effect of genetic variation on the interaction between diet and disease. Nutrigenetics has been used for decades in certain rare monogenic diseases such as phenylketonuria, and it has the potential to provide a basis for personalized dietary recommendations based on the individual's genetic makeup in order to prevent common multifactorial disorders decades before their clinical manifestation.
RECENT FINDINGS: Preliminary results regarding gene-diet interactions in cardiovascular diseases are for the most part inconclusive because of the limitations of current experimental designs. Success in this area will require the integration of various disciplines, and will require investigators to work on large population studies that are designed to investigate gene-environment interactions.
SUMMARY: Based on the current knowledge, we anticipate that in the future we will be able to harness the information contained in our genomes to achieve successful aging using behavioral changes, with nutrition being the cornerstone of this endeavor.
Mots-clé
Cardiovascular Diseases/etiology, Cardiovascular Diseases/genetics, Diet, Genome, Human, Genomics, Humans, Nutritional Physiological Phenomena
Pubmed
Web of science
Création de la notice
13/10/2013 22:01
Dernière modification de la notice
03/03/2018 21:37
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