Combination of androgen deprivation therapy and radiotherapy for localized prostate cancer in the contemporary era.

Détails

ID Serval
serval:BIB_C6A109D5D67B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Combination of androgen deprivation therapy and radiotherapy for localized prostate cancer in the contemporary era.
Périodique
Critical Reviews in Oncology/hematology
Auteur(s)
D'Angelillo R.M., Franco P., De Bari B., Fiorentino A., Arcangeli S., Alongi F.
ISSN
1879-0461 (Electronic)
ISSN-L
1040-8428
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
93
Numéro
2
Pages
136-148
Langue
anglais
Résumé
Currently, androgen deprivation therapy (ADT) has a well-defined role when administered together with radiotherapy (RT): neo-adjuvant and concurrent combination for intermediate risk-disease and adjuvant therapy for high risk disease. Evidence of this association was generated by randomized trials designed and led approximately 30 years ago; thus the question which arises is how relevant and portable are these data in our current clinical practice? In the present review, we examine the pitfalls of these published randomized controlled trials, their relevance to present daily clinics, where high-dose external beam RT or brachytherapy is applied, as well as the adoption of ADT in patients with concomitant cardiovascular disorders.
Pubmed
Web of science
Création de la notice
26/02/2015 20:27
Dernière modification de la notice
20/08/2019 15:42
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