Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays.

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Version: author
Serval ID
serval:BIB_C6511717BDEA
Type
Article: article from journal or magazin.
Collection
Publications
Title
Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays.
Journal
Plos One
Author(s)
Sala E., Guasch L., Iwaszkiewicz J., Mulero M., Salvadó M.J., Pinent M., Zoete V., Grosdidier A., Garcia-Vallvé S., Michielin O., Pujadas G.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Publication state
Published
Issued date
2011
Volume
6
Number
2
Pages
e16903
Language
english
Notes
Publication types: Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't ; Validation StudiesPublication Status: epublish
Keywords
Amino Acid Sequence, Biological Agents/analysis, Biological Agents/isolation & purification, Catalytic Domain/physiology, Computational Biology/methods, Enzyme Assays/methods, Enzyme Inhibitors/isolation & purification, Enzyme Inhibitors/pharmacology, High-Throughput Screening Assays/methods, Humans, I-kappa B Kinase/antagonists & inhibitors, I-kappa B Kinase/chemistry, Libraries, Digital, Models, Molecular, Molecular Sequence Data, Protein Structure, Secondary, Protein Structure, Tertiary/physiology, Reproducibility of Results, Sequence Homology, User-Computer Interface
Pubmed
Web of science
Open Access
Yes
Create date
07/02/2012 13:51
Last modification date
20/08/2019 15:41
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