Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays.

Détails

Ressource 1Télécharger: BIB_C6511717BDEA.P001.pdf (2512.89 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_C6511717BDEA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays.
Périodique
Plos One
Auteur(s)
Sala E., Guasch L., Iwaszkiewicz J., Mulero M., Salvadó M.J., Pinent M., Zoete V., Grosdidier A., Garcia-Vallvé S., Michielin O., Pujadas G.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Statut éditorial
Publié
Date de publication
2011
Volume
6
Numéro
2
Pages
e16903
Langue
anglais
Notes
Publication types: Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't ; Validation StudiesPublication Status: epublish
Mots-clé
Amino Acid Sequence, Biological Agents/analysis, Biological Agents/isolation & purification, Catalytic Domain/physiology, Computational Biology/methods, Enzyme Assays/methods, Enzyme Inhibitors/isolation & purification, Enzyme Inhibitors/pharmacology, High-Throughput Screening Assays/methods, Humans, I-kappa B Kinase/antagonists & inhibitors, I-kappa B Kinase/chemistry, Libraries, Digital, Models, Molecular, Molecular Sequence Data, Protein Structure, Secondary, Protein Structure, Tertiary/physiology, Reproducibility of Results, Sequence Homology, User-Computer Interface
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/02/2012 14:51
Dernière modification de la notice
09/05/2019 1:02
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