High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease.

Détails

ID Serval
serval:BIB_C56560CF6B14
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease.
Périodique
European Heart Journal
Auteur(s)
Plein S., Kozerke S., Suerder D., Luescher T.F., Greenwood J.P., Boesiger P., Schwitter J.
ISSN
1522-9645 (Electronic)
ISSN-L
0195-668X
Statut éditorial
Publié
Date de publication
2008
Volume
29
Numéro
17
Pages
2148-2155
Langue
anglais
Notes
Publication types: Comparative Study ; Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
AIMS: To evaluate the feasibility and diagnostic performance of high spatial resolution myocardial perfusion cardiac magnetic resonance (perfusion-CMR).
METHODS AND RESULTS: Fifty-four patients underwent adenosine stress perfusion-CMR. An in-plane spatial resolution of 1.4 × 1.4 mm(2) was achieved by using 5× k-space and time sensitivity encoding (k-t SENSE). Perfusion was visually graded for 16 left ventricular and two right ventricular (RV) segments on a scale from 0 = normal to 3 = abnormal, yielding a perfusion score of 0-54. Diagnostic accuracy of the perfusion score to detect coronary artery stenosis of >50% on quantitative coronary angiography was determined. Sources and extent of image artefacts were documented. Two studies (4%) were non-diagnostic because of k-t SENSE-related and breathing artefacts. Endocardial dark rim artefacts if present were small (average width 1.6 mm). Analysis by receiver-operating characteristics yielded an area under the curve for detection of coronary stenosis of 0.85 [95% confidence interval (CI) 0.75-0.95] for all patients and 0.82 (95% CI 0.65-0.94) and 0.87 (95% CI 0.75-0.99) for patients with single and multi-vessel disease, respectively. Seventy-four of 102 (72%) RV segments could be analysed.
CONCLUSION: High spatial resolution perfusion-CMR is feasible in a clinical population, yields high accuracy to detect single and multi-vessel coronary artery disease, minimizes artefacts and may permit the assessment of RV perfusion.
Mots-clé
Aged, Coronary Angiography, Coronary Artery Disease/diagnosis, Feasibility Studies, Female, Humans, Magnetic Resonance Angiography/methods, Male, Middle Aged, Myocardial Perfusion Imaging/methods, Observer Variation, ROC Curve, Sensitivity and Specificity
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/09/2011 17:54
Dernière modification de la notice
20/08/2019 16:40
Données d'usage