Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo.

Details

Serval ID
serval:BIB_C5423E50C43F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo.
Journal
Magnetic Resonance in Medicine
Author(s)
Gruetter R., Rothman D.L., Novotny E.J., Shulman R.G.
ISSN
0740-3194 (Print)
ISSN-L
0740-3194
Publication state
Published
Issued date
1992
Volume
25
Number
1
Pages
204-210
Language
english
Notes
Publication types: Journal Article ; Research Support, U.S. Gov't, P.H.S.Publication Status: ppublish
Abstract
Natural abundance 13C NMR spectra obtained from 144-cm3 volumes in the human brain contained well-resolved resonances of myo-inositol after 60 min of data accumulation. A mean concentration of 7.2 +/- 0.5 mumol/g (+/- SE, n = 7) was calculated from the comparison with phantoms. 13C NMR spectroscopy thus provides a complementary role in the quantitation of metabolites also observed in the crowded 1H spectrum.
Keywords
Adult, Brain/metabolism, Humans, Inositol/metabolism, Magnetic Resonance Spectroscopy/methods, Reference Values
Pubmed
Create date
04/08/2010 16:28
Last modification date
20/08/2019 16:40
Usage data