Anesthesia prevents auditory perceptual learning.

Détails

ID Serval
serval:BIB_C5066933EE18
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Anesthesia prevents auditory perceptual learning.
Périodique
Anesthesiology
Auteur(s)
Aberg K.C., Albrecht E., Tartaglia E.M., Farron A., Soom P., Herzog M.H.
ISSN
1528-1175[electronic]
Statut éditorial
Publié
Date de publication
2009
Volume
111
Numéro
5
Pages
1010-1015
Langue
anglais
Résumé
BACKGROUND: An auditory perceptual learning paradigm was used to investigate whether implicit memories are formed during general anesthesia. METHODS: Eighty-seven patients who had an American Society of Anesthesiologists physical status of I-III and were scheduled to undergo an elective surgery with general anesthesia were randomly assigned to one of two groups. One group received auditory stimulation during surgery, whereas the other did not. The auditory stimulation consisted of pure tones presented via headphones. The Bispectral Index level was maintained between 40 and 50 during surgery. To assess learning, patients performed an auditory frequency discrimination task after surgery, and comparisons were made between the groups. General anesthesia was induced with thiopental and maintained with a mixture of fentanyl and sevoflurane. RESULTS: There was no difference in the amount of learning between the two groups (mean +/- SD improvement: stimulated patients 9.2 +/- 11.3 Hz, controls 9.4 +/- 14.1 Hz). There was also no difference in initial thresholds (mean +/- SD initial thresholds: stimulated patients 31.1 +/- 33.4 Hz, controls 28.4 +/- 34.2 Hz). These results suggest that perceptual learning was not induced during anesthesia. No correlation between the bispectral index and the initial level of performance was found (Pearson r = -0.09, P = 0.59). CONCLUSION: Perceptual learning was not induced by repetitive auditory stimulation during anesthesia. This result may indicate that perceptual learning requires top-down processing, which is suppressed by the anesthetic.
Mots-clé
Implicit Memory, Cortical Reorganization, General-Anesthesia, Declarative Memory, Discrimination, Consciousness, Cortex, Sleep, Responses, Propofol
Pubmed
Web of science
Open Access
Oui
Création de la notice
12/11/2009 17:07
Dernière modification de la notice
20/08/2019 16:40
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