Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study.

Détails

ID Serval
serval:BIB_C42A179D0F3B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study.
Périodique
Europace
Auteur(s)
Felber Dietrich D., Schindler C., Schwartz J., Barthélémy J.C., Tschopp J.M., Roche F., von Eckardstein A., Brändli O., Leuenberger P., Gold D.R., Gaspoz J.M., Ackermann-Liebrich U., SAPALDIA Team
Contributeur(s)
SAPALDIA Team
ISSN
1099-5129 (Print)
ISSN-L
1099-5129
Statut éditorial
Publié
Date de publication
2006
Volume
8
Numéro
7
Pages
521-529
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural
Publication Status: ppublish
Résumé
AIMS: (i) To report associations between cardiovascular risk factors and heart rate variability (HRV) in a general population and (ii) to provide normal values for various HRV measurements in a healthy European general population sample aged >or=50.
METHODS AND RESULTS: Twenty-four-hour electrocardiograms were recorded in 1742 randomly selected SAPALDIA (Swiss cohort study on Air Pollution and Lung Diseases in Adults) participants aged >or=50. In multivariate regression analyses, women (n=895) had a 6.1% lower standard deviation of all normal RR (NN) intervals (SDNN), a 11.4% lower total power (TP), and a 27.2% lower low-frequency (LF) power than men (n=847). Per unit increase in BMI, SDNN decreased by 0.7% and TP decreased by 1.2%. Persons with high blood pressure had a 9.2% lower LF than normotensive persons and current smokers a 15.5% lower LF than never smokers. Each hour of heavy physical exercise was associated with a 2.0% increase in SDNN, a 3.6% increase in the high frequency (HF) range power and a 4.2% increase in LF power. Higher levels of uric acid, high-sensitive C-reactive protein and non-HDL-cholesterol were associated with lower TP, HF and LF. Percentiles of TP and LF/HF as a function of age were calculated for an asymptomatic subsample of participants (n=499) free of cardioactive medications.
CONCLUSION: Heart rate variability in a general population sample shows expected associations with all known cardiovascular risk factors, although not identically for all HRV domains. Together with our percentile estimates for HRV as a function of age, these findings could assist scientists in interpreting 24 h HRV values and factors influencing them in an ageing population.
Mots-clé
Aging/physiology, Analysis of Variance, Cardiovascular Diseases/physiopathology, Chi-Square Distribution, Cross-Sectional Studies, Electrocardiography, Ambulatory, Female, Heart Rate/physiology, Humans, Interviews as Topic, Life Style, Male, Reference Values, Regression Analysis, Risk Factors
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 10:50
Dernière modification de la notice
09/05/2019 0:55
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