Deficit in memory consolidation (abnormal forgetting rate) in childhood temporal lobe epilepsy. Pre and postoperative long-term observation.

Details

Serval ID
serval:BIB_C22B94EBF4E4
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Deficit in memory consolidation (abnormal forgetting rate) in childhood temporal lobe epilepsy. Pre and postoperative long-term observation.
Journal
Neuropediatrics
Author(s)
Cronel-Ohayon S., Zesiger P., Davidoff V., Boni A., Roulet E., Deonna T.
ISSN
0174-304X
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
37
Number
6
Pages
317-324
Language
english
Notes
Publication types: Case Reports ; Journal Article
Abstract
Deficits in memory consolidation have been reported in adult patients with epilepsy but, not to our knowledge, in children. We report the long-term follow-up (9 y. o. to 18 y. o.) of a boy who suffered from temporal lobe epilepsy and underwent a left temporal lobectomy with amygdalo-hippocampal resection at the age of 10. He showed an abnormal forgetting rate when trying to encode new information and a significant deficit for retrieving remote episodic memories (when compared with his twin brother), both consistent with a consolidation disorder. His memory condition slightly improved after cessation of the epilepsy, nevertheless did not normalize. No standard memory assessment could pinpoint his memory problem, hence an adapted methodology was needed. We discuss the nature of the memory deficit, its possible causes and its clinical implications.
Keywords
Adolescent, Amygdala/pathology, Amygdala/physiopathology, Anterior Temporal Lobectomy, Child, Diseases in Twins/diagnosis, Diseases in Twins/physiopathology, Dominance, Cerebral/physiology, Electroencephalography, Epilepsy, Temporal Lobe/diagnosis, Epilepsy, Temporal Lobe/physiopathology, Follow-Up Studies, Hippocampus/pathology, Hippocampus/physiopathology, Humans, Magnetic Resonance Imaging, Male, Memory Disorders/diagnosis, Memory Disorders/physiopathology, Memory, Short-Term/physiology, Mental Recall/physiology, Neurons/pathology, Neuropsychological Tests, Postoperative Complications/diagnosis, Postoperative Complications/physiopathology, Retention (Psychology)/physiology, Temporal Lobe/abnormalities, Temporal Lobe/pathology, Twins, Dizygotic
Pubmed
Web of science
Create date
12/01/2010 9:09
Last modification date
20/08/2019 15:37
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