Evaluation des conditions d'intubation sous rocuronium. [Assessment of intubation time and conditions under the influence of rocuronium]

Détails

ID Serval
serval:BIB_C0FA8189D750
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Evaluation des conditions d'intubation sous rocuronium. [Assessment of intubation time and conditions under the influence of rocuronium]
Périodique
Canadian Journal of Anaesthesia
Auteur(s)
Haller  G., Gardaz  J. P., Bissonnette  B.
ISSN
0832-610X (Print)
Statut éditorial
Publié
Date de publication
04/1998
Volume
45
Numéro
4
Pages
312-6
Notes
Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial --- Old month value: Apr
Résumé
PURPOSE: To evaluate the tracheal intubating conditions when intubation time is determined by the onset time of the neuromuscular block either of the adductor pollicis (AP) or of the orbicularis oculi muscle (OO). METHODS: In this prospective, double blind, randomised study, 40 adults ASA I-II undergoing general anaesthesia with tracheal intubation were allocated to two groups (n = 20) according to the reference muscle (AP or OO) used to determine the appropriate intubation time. Induction of anaesthesia was achieved with 5-7 mg.kg-1 thiopentone, 1.5-2.5 micrograms.kg-1 fentanyl and 0.9 mg.kg-1 rocuronium (3 x ED95) for muscular relaxation. Supramaximal train of four stimulation of the ulnar and facial nerve every 10 sec was used to monitor the neuromuscular block. After visual loss of AP or OO contraction, tracheal intubation and quality of intubation assessment were performed by two independent anaesthetists. Data are expressed as mean and standard error of the mean (X +/- SEM). RESULTS: Curarisation time of the OO was shorter (110 +/- 4.9 sec) than that of the AP (144 +/- 5.5 sec; P < 0.0001). Intubation conditions were excellent in 95% and good in 5% of the patients in the AP group whereas in the OO group only 65% of the patients had excellent and 20% good intubation conditions (P < 0.05). Coughing was observed in 15% of patients in the OO group during tracheal intubation. CONCLUSION: Monitoring neuro-muscular activity of the AP using TOF to determine the appropriate tracheal intubation time and conditions in patients paralysed with rocurorium is more clinically relevant than monitoring the OO muscle.
Mots-clé
Adult Androstanols/*pharmacology Double-Blind Method Humans *Intubation, Intratracheal Neuromuscular Nondepolarizing Agents/*pharmacology Prospective Studies
Pubmed
Web of science
Open Access
Oui
Création de la notice
28/01/2008 11:48
Dernière modification de la notice
09/05/2019 0:44
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