Das Antiarrhythmikum Chinidin als Alternative in der Behandlung der schweren Falciparum-Malaria. [The anti-arrhythmia drug quinidine as an alternative in the treatment of severe falciparum malaria]

Details

Serval ID
serval:BIB_BB34BBC79F44
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Das Antiarrhythmikum Chinidin als Alternative in der Behandlung der schweren Falciparum-Malaria. [The anti-arrhythmia drug quinidine as an alternative in the treatment of severe falciparum malaria]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Ris  H. B., Stahel  E., Pittet  J. F., Friedemann  M.
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
02/1983
Volume
113
Number
7
Pages
254-8
Notes
Case Reports
English Abstract
Journal Article --- Old url value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6340187 --- Old month value: Feb 19
Abstract
Parenteral quinine is the most effective treatment for severe falciparum malaria. It is not easily available in Switzerland and so dangerous delays treating patients may occur. The antiarrhythmic drug quinidine, usually stocked by hospitals, is an alternative drug for malaria treatment. We report the cases of two patients with severe malaria imported from Kenya. They were treated first with intravenous quinidine sulfate over 3 days and for another 4 days with peroral quinidine sulfate. The therapeutic response was excellent. During the 2 months posttherapeutic period no recrudescence of Plasmodium falciparum occurred. 20 mg/kg b.w./die of quinidine given intravenously seems to be an adequate dose in severe falciparum malaria.
Keywords
Administration, Oral Adult Anti-Arrhythmia Agents/administration & dosage/*therapeutic use Humans Injections, Intravenous Malaria/*drug therapy Male Middle Aged Plasmodium falciparum Quinidine/administration & dosage/*therapeutic use
Pubmed
Web of science
Create date
29/01/2008 13:00
Last modification date
20/08/2019 15:29
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