Association diclofenac-dexamethasone dans le traitement de l'inflammation postopératoire: étude prospective en double-insu [Diclofenac-dexamethasone combination in treatment of postoperative inflammation: prospective double-blind study].

Détails

ID Serval
serval:BIB_B86C550DD669
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Association diclofenac-dexamethasone dans le traitement de l'inflammation postopératoire: étude prospective en double-insu [Diclofenac-dexamethasone combination in treatment of postoperative inflammation: prospective double-blind study].
Périodique
Klinische Monatsblätter für Augenheilkunde
Auteur(s)
Othenin-Girard P., Borruat X., Bovey E., Pittet N., Herbort C.P.
ISSN
0023-2165 (Print)
ISSN-L
0023-2165
Statut éditorial
Publié
Date de publication
1992
Peer-reviewed
Oui
Volume
200
Numéro
5
Pages
362-366
Langue
français
Notes
Publication types: Clinical Trial ; English Abstract ; Journal Article ; Randomized Controlled Trial
Publication Status: ppublish
Résumé
In a prospective randomized double masked study including 40 patients we evaluated the anti-inflammatory effect of a combination of dexamethasone acetate 0.1% + diclofenac 0.1% drops compared to dexamethasone acetate 0.1% + placebo drops, after ECCE + posterior chamber lens implantation. Anterior chamber (AC) flare and cells were measured with the laser flare-cell meter Kowa FC-1000. The group receiving the dexamethasone-diclofenac combination showed a more rapid decrease of AC flare which was significant at days D3 (P less than 0.003) and D12 (p less than 0.028). The reduction of AC cells was comparable in both groups, showing however a strong tendency toward a lower cell count in the group receiving diclofenac at days D12 and D30 (p less than 0.08). Tolerance of diclofenac was good and comparable to the placebo.
Mots-clé
Aged, Anterior Chamber/drug effects, Dexamethasone/administration & dosage, Diclofenac/administration & dosage, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Inflammation/drug therapy, Lenses, Intraocular, Male, Middle Aged, Postoperative Complications/drug therapy
Pubmed
Web of science
Création de la notice
28/01/2008 12:40
Dernière modification de la notice
20/08/2019 15:26
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