Poorly Differentiated Neuroendocrine Carcinoma of the Sigmoid Tract in Long-Standing Ulcerative Colitis: Report of a Case and Review of the Literature.

Détails

ID Serval
serval:BIB_B41C2E431ACA
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Poorly Differentiated Neuroendocrine Carcinoma of the Sigmoid Tract in Long-Standing Ulcerative Colitis: Report of a Case and Review of the Literature.
Périodique
International journal of surgical pathology
Auteur(s)
Bolzacchini E., Chini C., Cortelezzi C.C., Vallini I., Pinotti G., La Rosa S., Uccella S.
ISSN
1940-2465 (Electronic)
ISSN-L
1066-8969
Statut éditorial
Publié
Date de publication
08/2018
Peer-reviewed
Oui
Volume
26
Numéro
5
Pages
479-483
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; Review
Publication Status: ppublish
Résumé
A 37-year-old male with long-standing and extensive ulcerative pancolitis developed a rapidly lethal poorly differentiated neuroendocrine carcinoma (NEC) in the sigmoid colon. Prior biopsies obtained from multiple sites of the colon during endoscopic surveillance showed minimal inflammatory changes and no sign of dysplasia. Patients with inflammatory bowel disease (IBD) are at increased risk of colorectal malignancies, and adenocarcinoma is the most common type of colorectal neoplasm associated with ulcerative colitis and Crohn's disease, but other types of epithelial and nonepithelial tumors have also been described in IBD. NECs arising in the setting of ulcerative colitis are very rare and are reported as anecdotic findings. We describe the clinicopathological features of an IBD-related NEC and review the previously reported cases.
Mots-clé
Adult, Anti-Inflammatory Agents/therapeutic use, Biomarkers, Tumor/blood, Biopsy, Carcinoma, Neuroendocrine/blood, Carcinoma, Neuroendocrine/diagnostic imaging, Carcinoma, Neuroendocrine/etiology, Carcinoma, Neuroendocrine/pathology, Colitis, Ulcerative/complications, Colitis, Ulcerative/diagnostic imaging, Colitis, Ulcerative/drug therapy, Colon, Sigmoid/diagnostic imaging, Colon, Sigmoid/pathology, Colonoscopy, Fatal Outcome, Humans, Male, Sigmoid Neoplasms/blood, Sigmoid Neoplasms/diagnostic imaging, Sigmoid Neoplasms/etiology, Sigmoid Neoplasms/pathology, Tomography, X-Ray Computed, cancer, inflammatory bowel disease, neuroendocrine carcinoma, ulcerative colitis
Pubmed
Web of science
Création de la notice
27/01/2018 11:20
Dernière modification de la notice
20/08/2019 15:22
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