Enhancement of Tissue Lesion Depth by Dual Wavelength Irradiation with the Nd-YAG/KTP Laser : Perspective for Laser Prostatectomy

Details

Serval ID
serval:BIB_B285C09DF26B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Enhancement of Tissue Lesion Depth by Dual Wavelength Irradiation with the Nd-YAG/KTP Laser : Perspective for Laser Prostatectomy
Journal
Lasers in Medical Science
Author(s)
Schmidlin  F., Delacrétaz  G., Oswald  M., Iselin  C., Jichlinski  P., Mermillod  B., Lemoine  R., Leisinger  H. J., Graber  P.
ISSN
0268-8921
Publication state
Published
Issued date
1997
Peer-reviewed
Oui
Volume
12
Number
4
Pages
364-370
Language
english
Abstract
The Nd-YAG/KTP laser coagulates and vaporizes prostate tissue. The objective of this study was to investigate the combined effects of both wavelengths and to determine the irradiation parameters allowing the largest lesion volume. Chicken breast tissue was irradiated ex vivo. Consecutive 1064 and 532 nm Nd-YAG/KTP laser irradiations were performed for different combinations (30 W/10 W, 20 W/20 W, 10 W/30 W) with variable total fluence (1200 J, 2400 J, 3600 J) and compared to isofluent single wavelengths at 40 W irradiation. The depths, diameters and volumes of the total lesion as well as the vaporization effects of the 532 nm wavelength on normal and on priorly coagulated tissue were analysed. Maximum total lesion depths (p< 0.001) were found under combined Nd-YAG/KTP (20 W/20 W) irradiation conditions. Ablation efficacy of the 532 nm wavelength was reduced after prior 1064 nm irradiation, but crater depths were increased. Dual wavelength irradiation with the Nd-YAG/KTP laser induces a specific denaturation process. This may represent a new approach to increase the depth of coagulation necrosis, and thus the treated volume, thereby improving long-term results.
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Create date
21/01/2008 16:11
Last modification date
20/08/2019 15:21
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