The impact of fasting on the interpretation of triglyceride levels for predicting myocardial infarction risk in HIV-positive individuals: the D:A:D study.

Details

Serval ID
serval:BIB_B03DB4258B88
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The impact of fasting on the interpretation of triglyceride levels for predicting myocardial infarction risk in HIV-positive individuals: the D:A:D study.
Journal
Journal of Infectious Diseases
Working group(s)
Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study
Contributor(s)
Kamara DA., Worm SW., Reiss P., Rickenbach M., Phillips A., Kirk O., D'Arminio Monforte A., Bruyand M., Law M., Wit SD., Smith CJ., Pradier C., Lundgren J., Sabin C.
ISSN
1537-6613 (Electronic)
ISSN-L
0022-1899
Publication state
Published
Issued date
2011
Volume
204
Number
4
Pages
521-525
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
Publication Status: ppublish
Abstract
We assessed whether fasting modifies the prognostic value of these measurements for the risk of myocardial infarction (MI). Analyses used mixed effect models and Poisson regression. After confounders were controlled for, fasting triglyceride levels were, on average, 0.122 mmol/L lower than nonfasting levels. Each 2-fold increase in the latest triglyceride level was associated with a 38% increase in MI risk (relative rate, 1.38; 95% confidence interval, 1.26-1.51); fasting status did not modify this association. Our results suggest that it may not be necessary to restrict analyses to fasting measurements when considering MI risk.
Keywords
Adult, Anti-HIV Agents/therapeutic use, Fasting/blood, Female, HIV Infections/blood, Humans, Male, Middle Aged, Myocardial Infarction/blood, Predictive Value of Tests, Retrospective Studies, Risk Factors, Triglycerides/blood
Pubmed
Web of science
Open Access
Yes
Create date
22/08/2011 15:05
Last modification date
20/08/2019 15:19
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