A Master's thesis.
Master (thesis) (master)
Neural correlates of motor abilities in 6 year old children born very preterm
BICKLE GRAZ M.
Université de Lausanne, Faculté de biologie et médecine
Number of pages
Children born very preterm are at risk of neurodevelopment disabilities, among them developmental coordination disorders (DCD). The aim of this study was to evaluate the association of motor scores obtained through a validates and standardized test, and brain metrics, in a cohort of very preterm infants assessed at the age of 6 years. Our study includes 29 children born between 2001 and 2003 at the University Hospital of Lausanne. Neonatal data, clinical motor development test results, and euro-imaging data were collected. The following neonatal data were correlated to development scores: sex, birthweight, in utero growth restriction and multiple pregnancy. There was mainly a strong and significant association of cortical thickness in the orbital and frontal lobes with adaptive motor tasks. Frontal lobe is involved in the executive control of behavior with premotor areas. Occipital lobe includes several areas responsible for visual functions. Regression analysis showed no significant association of segmentation or cortical areas with motor scores. In conclusion these preliminary results suggest that there is an association between visual processing and motor development, and that early intervention on this could be considered in the management of development coordination disorder.
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