Zweijähriger Knabe mit rezidivierenden mukokutanen Blutungen--Thrombasthenie Glanzmann. Die Rolle des Fibrinogenrezeptors (Glycoprotein IIb-IIIa) in der Thrombozytenfunktion [2-year-old boy with recurrent mucocutaneous hemorrhage--Glanzmann thrombasthenia. Role of the fibrinogen receptor (glycoprotein IIb-IIIa) in thrombocyte function].

Details

Serval ID
serval:BIB_A758A8B09AEF
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Zweijähriger Knabe mit rezidivierenden mukokutanen Blutungen--Thrombasthenie Glanzmann. Die Rolle des Fibrinogenrezeptors (Glycoprotein IIb-IIIa) in der Thrombozytenfunktion [2-year-old boy with recurrent mucocutaneous hemorrhage--Glanzmann thrombasthenia. Role of the fibrinogen receptor (glycoprotein IIb-IIIa) in thrombocyte function].
Journal
Therapeutische Umschau. Revue Thérapeutique
Author(s)
Alberio L., Hirt A.
ISSN
0040-5930 (Print)
ISSN-L
0040-5930
Publication state
Published
Issued date
1999
Peer-reviewed
Oui
Volume
56
Number
9
Pages
495-498
Language
german
Notes
Publication types: Case Reports ; English Abstract ; Journal Article Publication Status: ppublish
Abstract
We report the clinical history of a patient suffering from a mucocutaneous bleeding diathesis since his birth. Discussing this case of Glanzmann's thrombasthenia we present essential aspects of clinical approach, diagnostic procedures and management of patients with platelet dysfunctions. Furthermore, we summarize the current understanding of platelet involvement in the haemostatic process and we discuss the role of the fibrinogen receptor glycoprotein IIb-IIIa.
Keywords
Blood Coagulation Tests, Child, Preschool, Diagnosis, Differential, Hemorrhagic Disorders/blood, Hemorrhagic Disorders/etiology, Humans, Male, Platelet Aggregation/genetics, Platelet Aggregation/physiology, Platelet Glycoprotein GPIIb-IIIa Complex/genetics, Platelet Glycoprotein GPIIb-IIIa Complex/physiology, Thrombasthenia/blood, Thrombasthenia/diagnosis
Pubmed
Create date
10/02/2015 11:27
Last modification date
20/08/2019 15:12
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