Focal nodular hyperplasia: natural course observed with CT and MRI.
Details
Serval ID
serval:BIB_A31F4DF69E2D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Focal nodular hyperplasia: natural course observed with CT and MRI.
Journal
Journal of Computer Assisted Tomography
ISSN
0363-8715 (Print)
ISSN-L
0363-8715
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
24
Number
1
Pages
61-66
Language
english
Notes
Publication types: Comparative Study ; Journal ArticlePublication Status: ppublish
Abstract
PURPOSE: The purpose of this work was to assess the natural course of biopsy-proven focal nodular hyperplasia (FNH).
METHOD: Eighteen biopsy-proven FNHs in 14 patients (12 women and 2 men) who were followed for at least 6 months with CT and/or MRI were included in the study. The volume of the lesions was calculated twice by two observers using the summation of areas method. Intra- and interobserver variability was assessed by intraclass correlation coefficients. Longitudinal data analysis was performed with generalized estimating equations.
RESULTS: The volume of FNH was stable in 6 cases, decreased in 10 cases, and increased in 2 cases. Intra- and interobserver variability in size measurements was 5-10%. Intraclass correlation coefficients were >0.992. Longitudinal data analysis showed that there was a general trend of lesion regression.
CONCLUSION: Long-term follow-up and objective measurements performed in patients with biopsy-proven lesions show that the natural course of FNH is variable. In particular, lesion regression is not rare.
METHOD: Eighteen biopsy-proven FNHs in 14 patients (12 women and 2 men) who were followed for at least 6 months with CT and/or MRI were included in the study. The volume of the lesions was calculated twice by two observers using the summation of areas method. Intra- and interobserver variability was assessed by intraclass correlation coefficients. Longitudinal data analysis was performed with generalized estimating equations.
RESULTS: The volume of FNH was stable in 6 cases, decreased in 10 cases, and increased in 2 cases. Intra- and interobserver variability in size measurements was 5-10%. Intraclass correlation coefficients were >0.992. Longitudinal data analysis showed that there was a general trend of lesion regression.
CONCLUSION: Long-term follow-up and objective measurements performed in patients with biopsy-proven lesions show that the natural course of FNH is variable. In particular, lesion regression is not rare.
Keywords
Adolescent, Adult, Biopsy, Diagnosis, Differential, Female, Focal Nodular Hyperplasia/diagnosis, Humans, Liver/pathology, Liver/radiography, Magnetic Resonance Imaging, Male, Middle Aged, Observer Variation, Retrospective Studies, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
20/10/2016 16:35
Last modification date
20/08/2019 15:08