Focal nodular hyperplasia: natural course observed with CT and MRI.

Details

Serval ID
serval:BIB_A31F4DF69E2D
Type
Article: article from journal or magazin.
Collection
Publications
Title
Focal nodular hyperplasia: natural course observed with CT and MRI.
Journal
Journal of Computer Assisted Tomography
Author(s)
Leconte I., Van Beers B.E., Lacrosse M., Sempoux C., Jamart J., Materne R., Baudrez V., Horsmans Y.
ISSN
0363-8715 (Print)
ISSN-L
0363-8715
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
24
Number
1
Pages
61-66
Language
english
Notes
Publication types: Comparative Study ; Journal ArticlePublication Status: ppublish
Abstract
PURPOSE: The purpose of this work was to assess the natural course of biopsy-proven focal nodular hyperplasia (FNH).
METHOD: Eighteen biopsy-proven FNHs in 14 patients (12 women and 2 men) who were followed for at least 6 months with CT and/or MRI were included in the study. The volume of the lesions was calculated twice by two observers using the summation of areas method. Intra- and interobserver variability was assessed by intraclass correlation coefficients. Longitudinal data analysis was performed with generalized estimating equations.
RESULTS: The volume of FNH was stable in 6 cases, decreased in 10 cases, and increased in 2 cases. Intra- and interobserver variability in size measurements was 5-10%. Intraclass correlation coefficients were >0.992. Longitudinal data analysis showed that there was a general trend of lesion regression.
CONCLUSION: Long-term follow-up and objective measurements performed in patients with biopsy-proven lesions show that the natural course of FNH is variable. In particular, lesion regression is not rare.
Keywords
Adolescent, Adult, Biopsy, Diagnosis, Differential, Female, Focal Nodular Hyperplasia/diagnosis, Humans, Liver/pathology, Liver/radiography, Magnetic Resonance Imaging, Male, Middle Aged, Observer Variation, Retrospective Studies, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
20/10/2016 16:35
Last modification date
20/08/2019 15:08
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