DNA topology: feeling the pulse of a topoisomerase.
Details
Serval ID
serval:BIB_A2E67BFDAF75
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
DNA topology: feeling the pulse of a topoisomerase.
Journal
Current Biology
ISSN
0960-9822[print], 0960-9822[linking]
Publication state
Published
Issued date
07/2000
Volume
10
Number
14
Pages
R526-R528
Language
english
Notes
Publication types: In Vitro ; Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
The action of individual type II DNA topoisomerases has been followed in real time by observing the elastic response of single DNA molecules to sequential strand passage events. Micromanipulation methods provide a complementary approach to biochemical studies for investigating the mechanism of DNA topoisomerases.
Keywords
Adenosine Triphosphate/metabolism, Animals, DNA Topoisomerases, Type II/metabolism, DNA, Superhelical/chemistry, DNA, Superhelical/metabolism, Models, Biological, Nucleic Acid Conformation
Pubmed
Web of science
Open Access
Yes
Create date
24/01/2008 11:36
Last modification date
20/08/2019 16:08
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