Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy

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Serval ID
serval:BIB_A17284746A4C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Detection of JC virus by polymerase chain reaction in cerebrospinal fluid from two patients with progressive multifocal leukoencephalopathy
Journal
European Journal of Clinical Microbiology and Infectious Diseases
Author(s)
Telenti  A., Marshall  W. F., Aksamit  A. J., Smilack  J. D., Smith  T. F.
ISSN
0934-9723 (Print)
Publication state
Published
Issued date
03/1992
Volume
11
Number
3
Pages
253-4
Notes
Comparative Study
Journal Article --- Old month value: Mar
Abstract
The polymerase chain reaction (PCR) was used to identify JC virus (JCV) in the cerebrospinal fluid of two patients with progressive multifocal leukoencephalopathy confirmed by brain biopsy. In addition, JCV viremia was demonstrated by PCR in one case. JCV detection in spinal fluid by PCR may be the first non-invasive technique available for the diagnostic confirmation of progressive multifocal leukoencephalopathy.
Keywords
DNA, Viral/cerebrospinal fluid Humans JC Virus/*isolation & purification Leukoencephalopathy, Progressive Multifocal/*cerebrospinal fluid/microbiology Polymerase Chain Reaction Tumor Virus Infections/*cerebrospinal fluid/microbiology Viremia/*microbiology
OAI-PMH
oai:serval.unil.ch:BIB_A17284746A4C
DOI
10.1007/BF02098091
Pubmed
1317800
Web of science
A1992HT71300009
Create date
25/01/2008 15:45
Last modification date
20/08/2019 16:07
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