Low-dose, simple, and fast grating-based X-ray phase-contrast imaging.

Details

Serval ID
serval:BIB_99158CAE48D2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Low-dose, simple, and fast grating-based X-ray phase-contrast imaging.
Journal
Proceedings of the National Academy of Sciences of the United States of America
Author(s)
Zhu P., Zhang K., Wang Z., Liu Y., Liu X., Wu Z., McDonald S.A., Marone F., Stampanoni M.
ISSN
1091-6490[electronic], 0027-8424[linking]
Publication state
Published
Issued date
2010
Volume
107
Number
31
Pages
13576-13581
Language
english
Abstract
Phase sensitive X-ray imaging methods can provide substantially increased contrast over conventional absorption-based imaging and therefore new and otherwise inaccessible information. The use of gratings as optical elements in hard X-ray phase imaging overcomes some of the problems that have impaired the wider use of phase contrast in X-ray radiography and tomography. So far, to separate the phase information from other contributions detected with a grating interferometer, a phase-stepping approach has been considered, which implies the acquisition of multiple radiographic projections. Here we present an innovative, highly sensitive X-ray tomographic phase-contrast imaging approach based on grating interferometry, which extracts the phase-contrast signal without the need of phase stepping. Compared to the existing phase-stepping approach, the main advantages of this new method dubbed "reverse projection" are not only the significantly reduced delivered dose, without the degradation of the image quality, but also the much higher efficiency. The new technique sets the prerequisites for future fast and low-dose phase-contrast imaging methods, fundamental for imaging biological specimens and in vivo studies.
Keywords
Animals, Mice, Radiation Dosage, Radiography/methods, Rats, Time Factors, Tomography, X-Ray/methods
Pubmed
Web of science
Open Access
Yes
Create date
14/09/2010 10:54
Last modification date
20/08/2019 16:00
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