Biosynthesis of glycophosphoinositol anchors in Saccharomyces cerevisiae.

Details

Serval ID
serval:BIB_979114102EEB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Biosynthesis of glycophosphoinositol anchors in Saccharomyces cerevisiae.
Journal
Cell Biology International Reports
Author(s)
Conzelmann A., Fankhauser C., Puoti A., Desponds C.
ISSN
0309-1651[print], 0309-1651[linking]
Publication state
Published
Issued date
09/1991
Volume
15
Number
9
Pages
863-873
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
Numerous membrane glycoproteins of Saccharomyces cerevisiae are posttranslationally modified by the addition of a glycophosphatidylinositol (GPI). These proteins can be detected most easily by metabolic labelling of yeast cells with 3H-myoinositol or 3H-palmitate. This report summarizes what little is known about the identity, biosynthesis and cellular localization of GPI-modified glycoproteins in Saccharomyces cerevisiae as well as what could be learned from the system with respect to the biosynthesis of GPI's in general.
Keywords
Electrophoresis, Polyacrylamide Gel, Glycosylphosphatidylinositols, Membrane Glycoproteins/chemistry, Mutation, Phosphatidylinositols/biosynthesis, Polysaccharides/biosynthesis, Saccharomyces cerevisiae/chemistry
Pubmed
Web of science
Create date
24/01/2008 16:29
Last modification date
20/08/2019 15:59
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