Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.

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serval:BIB_96EA05644DFC
Type
Article: article from journal or magazin.
Publication sub-type
Minutes: analyse of a published work.
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Title
Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.
Journal
Nature Communications
Author(s)
Benoit J.B., Adelman Z.N., Reinhardt K., Dolan A., Poelchau M., Jennings E.C., Szuter E.M., Hagan R.W., Gujar H., Shukla J.N., Zhu F., Mohan M., Nelson D.R., Rosendale A.J., Derst C., Resnik V., Wernig S., Menegazzi P., Wegener C., Peschel N., Hendershot J.M., Blenau W., Predel R., Johnston P.R., Ioannidis P., Waterhouse R.M., Nauen R., Schorn C., Ott M.C., Maiwald F., Johnston J.S., Gondhalekar A.D., Scharf M.E., Peterson B.F., Raje K.R., Hottel B.A., Armisén D., Crumière A.J., Refki P.N., Santos M.E., Sghaier E., Viala S., Khila A., Ahn S.J., Childers C., Lee C.Y., Lin H., Hughes D.S., Duncan E.J., Murali S.C., Qu J., Dugan S., Lee S.L., Chao H., Dinh H., Han Y., Doddapaneni H., Worley K.C., Muzny D.M., Wheeler D., Panfilio K.A., Vargas Jentzsch I.M., Vargo E.L., Booth W., Friedrich M., Weirauch M.T., Anderson M.A., Jones J.W., Mittapalli O., Zhao C., Zhou J.J., Evans J.D., Attardo G.M., Robertson H.M., Zdobnov E.M., Ribeiro J.M., Gibbs R.A., Werren J.H., Palli S.R., Schal C., Richards S.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
7
Pages
10165
Language
english
Abstract
The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite.
Keywords
Animals, Bedbugs/genetics, Ectoparasitic Infestations, Feeding Behavior, Gene Transfer, Horizontal/genetics, Genome, Host-Parasite Interactions/genetics, Humans, Insecticide Resistance/genetics, Insecticides, Sequence Analysis, DNA
DOI
10.1038/ncomms10165
Pubmed
26836814
Web of science
000371010800002
Open Access
Yes
Create date
20/09/2017 9:58
Last modification date
03/01/2020 18:43
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