Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.

Détails

Ressource 1Télécharger: ncomms10165.pdf (977.44 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_96EA05644DFC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.
Périodique
Nature Communications
Auteur(s)
Benoit J.B., Adelman Z.N., Reinhardt K., Dolan A., Poelchau M., Jennings E.C., Szuter E.M., Hagan R.W., Gujar H., Shukla J.N., Zhu F., Mohan M., Nelson D.R., Rosendale A.J., Derst C., Resnik V., Wernig S., Menegazzi P., Wegener C., Peschel N., Hendershot J.M., Blenau W., Predel R., Johnston P.R., Ioannidis P., Waterhouse R.M., Nauen R., Schorn C., Ott M.C., Maiwald F., Johnston J.S., Gondhalekar A.D., Scharf M.E., Peterson B.F., Raje K.R., Hottel B.A., Armisén D., Crumière A.J., Refki P.N., Santos M.E., Sghaier E., Viala S., Khila A., Ahn S.J., Childers C., Lee C.Y., Lin H., Hughes D.S., Duncan E.J., Murali S.C., Qu J., Dugan S., Lee S.L., Chao H., Dinh H., Han Y., Doddapaneni H., Worley K.C., Muzny D.M., Wheeler D., Panfilio K.A., Vargas Jentzsch I.M., Vargo E.L., Booth W., Friedrich M., Weirauch M.T., Anderson M.A., Jones J.W., Mittapalli O., Zhao C., Zhou J.J., Evans J.D., Attardo G.M., Robertson H.M., Zdobnov E.M., Ribeiro J.M., Gibbs R.A., Werren J.H., Palli S.R., Schal C., Richards S.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
7
Pages
10165
Langue
anglais
Résumé
The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite.

Mots-clé
Animals, Bedbugs/genetics, Ectoparasitic Infestations, Feeding Behavior, Gene Transfer, Horizontal/genetics, Genome, Host-Parasite Interactions/genetics, Humans, Insecticide Resistance/genetics, Insecticides, Sequence Analysis, DNA
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/09/2017 9:58
Dernière modification de la notice
08/05/2019 22:22
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