Maturation of the lymphoid system. III. Induction of selective unresponsiveness by injection of a haptenated carbohydrate into neonatal mice.
Details
Serval ID
serval:BIB_93CCBAC9484C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Maturation of the lymphoid system. III. Induction of selective unresponsiveness by injection of a haptenated carbohydrate into neonatal mice.
Journal
Developmental and Comparative Immunology
ISSN
0145-305X (Print)
ISSN-L
0145-305X
Publication state
Published
Issued date
1983
Volume
7
Number
1
Pages
159-168
Language
english
Abstract
Neonatal treatment of A/J mice with DNP-Ficoll reduced or eliminated indirect anti-DNP PFC normally produced in response to adult challenge with DNP-keyhole limpet hemocyanin. The remaining direct anti-DNP PFC response was of low avidity. Spleen cells from neonatal A/J mice inhibited the in vitro but not the in vivo response of adult spleen cells to DNP-Ficoll.
Keywords
Animals, Animals, Newborn, Antibody Formation, Antigens/immunology, Ficoll/analogs & derivatives, Ficoll/immunology, Hemocyanin, Hemolytic Plaque Technique, Immune Tolerance, Lymphoid Tissue/immunology, Mice, Mice, Inbred A, Polysaccharides/immunology, Spleen/immunology
Pubmed
Web of science
Create date
24/01/2008 15:54
Last modification date
20/08/2019 15:56
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