Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse

Details

Serval ID
serval:BIB_8FEA4B413DCA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse
Journal
Genetics
Author(s)
Keitges  E. A., Schorderet  D. F., Gartler  S. M.
ISSN
0016-6731 (Print)
Publication state
Published
Issued date
07/1987
Volume
116
Number
3
Pages
465-8
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jul
Abstract
Dosage studies and the inheritance pattern of the gene for steroid sulfatase (Sts) in the mouse have previously provided indirect evidence for a functional Y-linked allele which recombines obligatorily with its X-linked allele in male meiosis. In this study, we have investigated the linkage relationship of Sts and the sex-reversed mutation (Sxr), a gene which is known to reside in the pairing region of the Y chromosome. The results clearly demonstrate that Sxr and Sts are linked in a region of obligatory recombination and Sts maps proximal to Sxr with most recombinants occurring proximal to the two genes.
Keywords
Alleles Animals Linkage (Genetics) Mice Recombination, Genetic *Sex Chromosomes *Sex Determination (Analysis) Steryl-Sulfatase Sulfatases/*genetics
Pubmed
Web of science
Create date
28/01/2008 12:58
Last modification date
20/08/2019 14:53
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