Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse

Détails

ID Serval
serval:BIB_8FEA4B413DCA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse
Périodique
Genetics
Auteur(s)
Keitges  E. A., Schorderet  D. F., Gartler  S. M.
ISSN
0016-6731 (Print)
Statut éditorial
Publié
Date de publication
07/1987
Volume
116
Numéro
3
Pages
465-8
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jul
Résumé
Dosage studies and the inheritance pattern of the gene for steroid sulfatase (Sts) in the mouse have previously provided indirect evidence for a functional Y-linked allele which recombines obligatorily with its X-linked allele in male meiosis. In this study, we have investigated the linkage relationship of Sts and the sex-reversed mutation (Sxr), a gene which is known to reside in the pairing region of the Y chromosome. The results clearly demonstrate that Sxr and Sts are linked in a region of obligatory recombination and Sts maps proximal to Sxr with most recombinants occurring proximal to the two genes.
Mots-clé
Alleles Animals Linkage (Genetics) Mice Recombination, Genetic *Sex Chromosomes *Sex Determination (Analysis) Steryl-Sulfatase Sulfatases/*genetics
Pubmed
Web of science
Création de la notice
28/01/2008 13:58
Dernière modification de la notice
03/03/2018 19:23
Données d'usage