From radiobiology to technology: what is changing in radiotherapy for prostate cancer.

Détails

ID Serval
serval:BIB_8A495E1A7F50
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
From radiobiology to technology: what is changing in radiotherapy for prostate cancer.
Périodique
Expert Review of Anticancer Therapy
Auteur(s)
De Bari B., Fiorentino A., Arcangeli S., Franco P., D'Angelillo R.M., Alongi F.
ISSN
1744-8328 (Electronic)
ISSN-L
1473-7140
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
14
Numéro
5
Pages
553-564
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish Publication type : Review
Résumé
In the last decades, new technologies have been introduced in the daily clinical practice of the radiation oncologist: 3D-Conformal radiotherapy (RT) became almost universally available, thereafter, intensity modulated RT (IMRT) gained large diffusion, due to its potential impact in improving the clinical outcomes, and more recently, helical and volumetric arc IMRT with image-guided RT are becoming more and more diffused and used for prostate cancer patients. The conventional dose-fractionation results to be the best compromise between the efficacy and the safety of the treatment, but combining new techniques, modern RT allows to overcame one of the major limits of the 'older' RT: the impossibility of delivering higher total doses and/or high dose/fraction. The evidences regarding radiobiology, clinical and technological evolution of RT in prostate cancer have been reported and discussed.
Mots-clé
Humans, Male, Prostatic Neoplasms/radiotherapy, Radiotherapy/methods
Pubmed
Web of science
Création de la notice
20/01/2015 19:53
Dernière modification de la notice
03/03/2018 19:09
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