Living/non-living dissociation in a case of semantic dementia: a SPECT activation study.

Détails

ID Serval
serval:BIB_89D31417F634
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Living/non-living dissociation in a case of semantic dementia: a SPECT activation study.
Périodique
Neuropsychologia
Auteur(s)
Cardebat D., Demonet J.F., Celsis P., Puel M.
ISSN
0028-3932 (Print)
ISSN-L
0028-3932
Statut éditorial
Publié
Date de publication
1996
Peer-reviewed
Oui
Volume
34
Numéro
12
Pages
1175-1179
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
A category-specific dissociation with massive deficits in semantic knowledge of animals and preservation of knowledge of objects was observed in a demented patient with a left inferior temporal cortical atrophy responsible for a deficit of visual semantic processing. When the patient successfully processed the semantic feature of aurally presented object names, a SPECT study showed an activation of the left posterior and middle temporal cortex (Wernicke's area). This haemodynamic pattern was not observed during an unsuccessful processing of animal names that was associated with an activation of the left and right inferior frontal regions. Activation in Wernicke's area probably reflects an adequate matching between auditory lexical input and semantic knowledge for entities with multimodal representations, such as man-made objects. Activation in Broca's area and its right homologous region may correspond to an unsuccessful phonological strategy to evoke semantic features of animals, a category that is mainly visually represented.
Mots-clé
Aged, Arousal/physiology, Atrophy, Concept Formation, Dementia/physiopathology, Dementia/psychology, Dominance, Cerebral/physiology, Female, Humans, Mental Recall/physiology, Neuropsychological Tests, Regional Blood Flow/physiology, Semantics, Speech Perception/physiology, Temporal Lobe/pathology, Temporal Lobe/physiopathology, Tomography, Emission-Computed, Single-Photon
Pubmed
Web of science
Création de la notice
24/03/2013 17:36
Dernière modification de la notice
20/08/2019 15:48
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