A pilot assessment of alpha-stat vs pH-stat arterial blood gas analysis after cardiac arrest.

Détails

ID Serval
serval:BIB_87BCA8B2B09D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
A pilot assessment of alpha-stat vs pH-stat arterial blood gas analysis after cardiac arrest.
Périodique
Journal of Critical Care
Auteur(s)
Eastwood G.M., Suzuki S., Lluch C., Schneider A.G., Bellomo R.
ISSN
1557-8615 (Electronic)
ISSN-L
0883-9441
Statut éditorial
Publié
Date de publication
10/2015
Peer-reviewed
Oui
Volume
30
Numéro
1
Pages
138-144
Langue
anglais
Résumé
PURPOSE: Resuscitated cardiac arrest (CA) patients typically receive therapeutic hypothermia, but arterial blood gases (ABGs) are often assessed after adjustment to 37°C (alpha-stat) instead of actual body temperature (pH-stat). We sought to compare alpha-stat and pH-stat assessment of Pao2 and Paco2 in such patients.
MATERIALS AND METHODS: Using ABG data obtained during the first 24 hours of intensive care unit admission, we determined the impact of measured alpha vs calculated pH-stat on Pao2 and Paco2 on patient classification and outcomes for CA patients.
RESULTS: We assessed 1013 ABGs from 120 CA patients with a median age of patients 66 years (interquartile range, 50-76). Median alpha-stat Pao2 changed from 122 (95-156) to 107 (82-143) mm Hg with pH-stat and median Paco2 from 39 (34-46) to 35 (30-41) mm Hg (both P < .001). Using the categories of hyperoxemia, normoxemia, and hypoxemia, pH-stat estimation of Pao2 reclassified approximately 20% of patients. Using the categories of hypercapnia, normocapnia, and hypocapnia, pH stat estimation of Paco2 reclassified approximately 40% of patients. The mortality of patients in different Pao2 and Paco2 categories was similar for pH-stat and alpha-stat.
CONCLUSIONS: Using the pH-stat method, fewer resuscitated CA patients admitted to intensive care unit were classified as hyperoxemic or hypercapnic compared with alpha-stat. These findings suggest an impact of ABG assessment methodology on Pao2, Paco2, and patient classification but not on associated outcomes.
Pubmed
Web of science
Création de la notice
27/11/2014 9:15
Dernière modification de la notice
03/03/2018 19:02
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