Physiopathologie de l'hypertrophie ventriculaire gauche. [Physiopathology of left ventricular hypertrophy]

Details

Serval ID
serval:BIB_863B1CEA2DBA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Physiopathologie de l'hypertrophie ventriculaire gauche. [Physiopathology of left ventricular hypertrophy]
Journal
Archives des Maladies du Coeur et des Vaisseaux
Author(s)
Waeber B., Weber R., Brunner  H. R.
ISSN
0003-9683
Publication state
Published
Issued date
1995
Peer-reviewed
Oui
Volume
88 Spec No 2
Pages
9-14
Language
french
Abstract
Left ventricular hypertrophy (LVH) is an early complication of hypertension. To a certain degree, this process counteracts the parietal stress induced by high blood pressure. Genetic factors, obesity, high salt diet and different growth factors, notably angiotensin II and noradrenaline, can also predispose to hypertrophic cardiomyopathy. Left ventricular mass is increased on echocardiography in about 20% of hypertensive subjects. LVH is initially associated with a change in myocardial diastolic function and later with abnormal systolic function. It is a major risk factor, a cause of cardiac failure, reduction in coronary reserve and of ventricular arrhythmias. Treatment of hypertension is associated with regression of LVH and preservation or improvement in myocardial diastolic and systolic functions. The decrease in left ventricular mass could reduce the incidence of cardiovascular complications in hypertension.
Keywords
ElectrocardiographyHumansHypertension/complications/therapyHypertrophy, Left Ventricular/complications/*physiopathology/therapy
Pubmed
Web of science
Create date
06/03/2009 12:01
Last modification date
20/08/2019 14:45
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