Which clinical signs predict hypoxaemia in young Senegalese children with acute lower respiratory tract disease?

Details

Serval ID
serval:BIB_82F51EBBA177
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Which clinical signs predict hypoxaemia in young Senegalese children with acute lower respiratory tract disease?
Journal
Paediatrics and International Child Health
Author(s)
Wandeler G., Pauchard J.Y., Zangger E., Diawara H., Gehri M.
ISSN
2046-9055 (Electronic)
ISSN-L
2046-9047
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
35
Number
1
Pages
65-68
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
BACKGROUND: Acute lower respiratory tract diseases are an important cause of mortality in children in resource-limited settings. In the absence of pulse oximetry, clinicians rely on clinical signs to detect hypoxaemia.
OBJECTIVE: To assess the diagnostic value of clinical signs of hypoxaemia in children aged 2 months to 5 years with acute lower respiratory tract disease.
METHODS: Seventy children with a history of cough and signs of respiratory distress were enrolled. Three experienced physicians recorded clinical signs and oxygen saturation by pulse oximetry. Hypoxaemia was defined as oxygen saturation <90%. Clinical predictors of hypoxaemia were evaluated using adjusted diagnostic odds ratios (aDOR).
RESULTS: There was a 43% prevalence of hypoxaemia. An initial visual impression of poor general status [aDOR 20·0, 95% CI 3·8-106], severe chest-indrawing (aDOR 9·8, 95% CI 1·5-65), audible grunting (aDOR 6·9, 95% CI 1·4-25) and cyanosis (aDOR 26·5, 95% CI 1·1-677) were significant predictors of hypoxaemia.
CONCLUSION: In children under 5 years of age, several simple clinical signs are reliable predictors of hypoxaemia. These should be included in diagnostic guidelines.
Pubmed
Web of science
Create date
29/01/2015 20:12
Last modification date
20/08/2019 14:42
Usage data