Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Die orale Antikoagulation mit Vitamin K-Antagonisten [Oral anticoagulation with vitamin K antagonists].
Therapeutische Umschau. Revue Thérapeutique
Publication types: Comparative Study ; English Abstract ; Journal Article ; Review Publication Status: ppublish
Coumarins are broadly employed in clinical practice and should therefore belong to the group of 'well known' drugs. The present review will deal with some concepts of anticoagulant therapy: the role of vitamin K in the synthesis of functional coagulation factors, some clinically relevant pharmacokinetic aspects of coumarins, the management of oral anticoagulant therapy with special emphasis on the laboratory monitoring, and the most frequent complication, bleeding.
Acenocoumarol/administration & dosage, Acenocoumarol/adverse effects, Administration, Oral, Anticoagulants/administration & dosage, Anticoagulants/adverse effects, Blood Coagulation/physiology, Blood Coagulation Factors/physiology, Blood Coagulation Tests, Coumarins/administration & dosage, Coumarins/adverse effects, Drug Interactions, Hemorrhage/chemically induced, Humans, Phenprocoumon/administration & dosage, Phenprocoumon/adverse effects, Vitamin K/antagonists & inhibitors, Vitamin K/physiology
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