Rapid coagglutination test for the direct detection of group A streptococci from throat swabs.

Détails

ID Serval
serval:BIB_81894F93F2C2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Rapid coagglutination test for the direct detection of group A streptococci from throat swabs.
Périodique
European Journal of Clinical Microbiology
Auteur(s)
Ogay K., Bille J.
ISSN
0722-2211 (Print)
ISSN-L
0722-2211
Statut éditorial
Publié
Date de publication
1986
Volume
5
Numéro
3
Pages
317-319
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Résumé
A one-minute antigen detection test was compared with a conventional culture method for detecting group A beta-hemolytic streptococci. The test detects coagglutination between protein A and streptococcal antigen extracted directly from throat swabs. Of the 307 specimens tested, 66 (21.5%) were positive for group A streptococci by culture and 16 specimens (5.2%) were positive for other beta-hemolytic streptococci. The direct test agreed with the culture in 274 of 307 specimens (accuracy 89.3%). The sensitivity of the test was 86.4% (57/66), the specificity 90% (217/241), the positive predictive value 70.4% and the negative predictive value 96%. If only throat cultures with more than 100 colonies of group A streptococci per plate were considered, the sensitivity of the direct test rose to 96%. If only a strong agglutination was considered positive, the specificity of the direct test rose to 98%. Further studies are needed to determine whether this test could be used alone or in addition to culture.
Mots-clé
Agglutination Tests, Antigens, Bacterial/analysis, Humans, Pharyngitis/microbiology, Pharynx/microbiology, Streptococcal Infections/diagnosis, Streptococcal Infections/microbiology, Streptococcus pyogenes/immunology, Streptococcus pyogenes/isolation & purification
Pubmed
Web of science
Création de la notice
11/02/2008 13:39
Dernière modification de la notice
03/03/2018 18:48
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