Pharmacological studies on meprobamate incorporation in human beard hair.

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Serval ID
serval:BIB_8022DBB1FEB7
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
Pharmacological studies on meprobamate incorporation in human beard hair.
Journal
International Journal of Legal Medicine
Author(s)
Kintz P., Tracqui A., Mangin P.
ISSN
0937-9827[print], 0937-9827[linking]
Publication state
Published
Issued date
1993
Volume
105
Number
5
Pages
283-287
Language
english
Abstract
The time course of appearance of meprobamate in beard hair after single oral administration (400, 800, or 1200 mg) was monitored in 3 groups of 4 subjects by GC/MS. Meprobamate appeared in beard hair approximately 4-5 days after administration and peaked during the 7-9th day. Drug levels in beard hair appeared to be dose-related.
Keywords
Administration, Oral, Adult, Dose-Response Relationship, Drug, Gas Chromatography-Mass Spectrometry, Hair/metabolism, Humans, Male, Meprobamate/administration & dosage, Meprobamate/pharmacokinetics, Metabolic Clearance Rate/physiology
Pubmed
8471546
Create date
18/10/2010 14:59
Last modification date
20/08/2019 15:40
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