Hepatitis C. [Hepatitis C]

Détails

ID Serval
serval:BIB_7F3AEC667945
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Hepatitis C. [Hepatitis C]
Périodique
Therapeutische Umschau
Auteur(s)
Moradpour  D., Blum  H. E.
ISSN
0040-5930 (Print)
Statut éditorial
Publié
Date de publication
08/2004
Volume
61
Numéro
8
Pages
493-8
Notes
Comparative Study
English Abstract
Journal Article
Review --- Old month value: Aug
Résumé
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Here, we briefly review the virology, diagnosis and therapy of hepatitis C. Standard therapy with pegylated interferon-alpha and ribavirin results in a sustained virological response in 40-50% of genotype 1- and in about 80% of genotype 2- or 3-infected patients. Recent progress has allowed the identification of novel antiviral targets and therapeutic strategies. These will likely complement existing therapeutic modalities in the near future.
Mots-clé
Acute Disease Antiviral Agents/administration & dosage/therapeutic use Carcinoma, Hepatocellular/etiology Drug Therapy, Combination Genotype Hepacivirus/genetics *Hepatitis C/complications/diagnosis/drug therapy/epidemiology/virology Hepatitis C, Chronic/complications/diagnosis/drug therapy/epidemiology/virology Humans Interferon-alpha/administration & dosage/therapeutic use Liver Cirrhosis/etiology Liver Neoplasms/etiology Liver Transplantation RNA, Viral/analysis Reverse Transcriptase Polymerase Chain Reaction Ribavirin/administration & dosage/therapeutic use Time Factors
Pubmed
Création de la notice
25/01/2008 17:05
Dernière modification de la notice
03/03/2018 18:43
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