Fetal lung growth in experimental utero-abdominal pregnancy

Détails

ID Serval
serval:BIB_7C988CF5706C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Fetal lung growth in experimental utero-abdominal pregnancy
Périodique
Obstetrics and Gynecology
Auteur(s)
Moessinger  A. C.
ISSN
0029-7844 (Print)
Statut éditorial
Publié
Date de publication
11/1986
Volume
68
Numéro
5
Pages
675-8
Notes
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: Nov
Résumé
We removed rat fetuses from the uterus without disturbing the placental implantation site, placing the fetuses in the peritoneal cavity either within intact membranes (with or without amniotic fluid) or outside of the fetal membranes. Untouched littermate fetuses served as controls. The surgery was performed on day 17 of gestation and the outcome was analyzed at term, 4 days later. The utero-abdominal pregnancies with intact membranes and amniotic fluid yielded fetuses in all respects indistinguishable from littermate controls. Extrauterine fetuses maintained within their membranes but without amniotic fluid as well as extrauterine and extramembranous fetuses displayed identical features: body weight was slightly reduced; after correction for body weight, only their lungs weighed significantly less and contained less deoxyribonucleic acid. In addition, fetuses in these two groups had multiple joint contractures and occasional webbing of the skin. These experimental findings in rats indicate an important role of amniotic fluid in fetal development, especially of the lung.
Mots-clé
Amniotic Fluid/*physiology Animals Body Weight DNA/analysis Extraembryonic Membranes/*physiology Female Fetal Organ Maturity Lung/analysis/*embryology Pregnancy Pregnancy, Abdominal/*physiopathology Rats
Pubmed
Web of science
Création de la notice
25/01/2008 14:16
Dernière modification de la notice
03/03/2018 18:37
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