Physiological profile during venovenous perfusion in dogs using a polypropylene membrane lung with secondary flows

Détails

ID Serval
serval:BIB_7A2EA78A4256
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Physiological profile during venovenous perfusion in dogs using a polypropylene membrane lung with secondary flows
Périodique
Journal of Biomedical Engineering
Auteur(s)
Gardaz  J. P., Dorrington  K. L., Py  P., Schweizer  A.
ISSN
0141-5425 (Print)
Statut éditorial
Publié
Date de publication
01/1988
Volume
10
Numéro
1
Pages
74-81
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Résumé
Venovenous perfusion has been conducted in 12 healthy dogs to examine carbon dioxide (CO2) transfer and haemocompatibility over 9 h during total extracorporeal CO2 removal using a microporous polypropylene membrane lung with secondary flows in the blood channel. The anaesthetized animals were maintained normocapnic by including CO2 in the inspired gases. The CO2 removal was achieved using 0.631 m2 of active membrane, at a pulsatile Reynolds number of 50, and a CO2 extraction from blood of 17.8 ml (STP) dl-1. Gas exchange remained constant during the perfusions. Several aspects of our results suggest that the haemocompatibility of a system of the kind used here is at least as favourable as that of a steady flow device using a continuous silicone rubber membrane of equivalent gas transfer capability.
Mots-clé
Animals Dogs *Extracorporeal Circulation Hemodynamic Processes Hemoglobins/analysis Leukocyte Count *Membranes, Artificial Polyethylenes *Pulmonary Circulation *Pulmonary Gas Exchange
Pubmed
Web of science
Création de la notice
28/01/2008 11:48
Dernière modification de la notice
03/03/2018 18:33
Données d'usage