Evolution of paced QRS and QTc intervals in children with epicardial pacing leads.

Détails

ID Serval
serval:BIB_76180751F2FD
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Evolution of paced QRS and QTc intervals in children with epicardial pacing leads.
Périodique
Clinical Research in Cardiology
Auteur(s)
Tomaske M., Harpes P., Prêtre R., Dodge-Khatami A., Bauersfeld U.
ISSN
1861-0684 (Print)
ISSN-L
1861-0684
Statut éditorial
Publié
Date de publication
2007
Peer-reviewed
Oui
Volume
96
Numéro
11
Pages
787-793
Langue
anglais
Résumé
AIMS: Permanent ventricular pacing in children is associated with ventricular dysfunction due to asynchronous activation. It is unclear whether paced QRS intervals increase disproportionately over time, which could potentially cause ventricular dysfunction.
METHODS: A total of 52 children, with bipolar steroideluting epicardial leads implanted at a median age of 5.6 years (0.0-17.4), was analyzed and followed up to 12.2 years (median 3.7). Patients were subdivided in two groups: right (RV, n = 21) and left (LV, n = 31) ventricular pacing. To correct for age, standard deviation scores (Z-scores) for paced QRS and QTc intervals were calculated from published standard-ECG norm-values. As a measure for individual paced QRS and QTc interval changes, a regression slope coefficient (incline(i)) was calculated for each patient's course.
RESULTS: Mean Z-scores for paced QRS intervals at first and last follow-up were 4.7 +/- 1.2 and 4.9 +/- 0.9 for group RV, 4.4 +/- 1.1 and 4.8 +/- 1.1 for group LV. Incline(i) of paced QRS (group RV: 0.038 [-0.27-0.12], group LV: 0.147 [-0.05-0.30]; p = 0.07) and QTc intervals (group RV: 0.026 [-0.08-0.06], group LV: 0.023 [-0.04-0.09]; p = 0.63) did not differ between both groups and indicated limited interval changes over time.
CONCLUSION: Neither epicardial pacing of the right nor left ventricle caused disproportionate paced QRS or QTc interval increases over time. An age-related prolongation of the electrical activation unlikely causes ventricular dysfunction.
Pubmed
Web of science
Création de la notice
16/12/2014 20:17
Dernière modification de la notice
03/03/2018 18:24
Données d'usage