Detectable thyroglobulin with negative imaging in differentiated thyroid cancer patients. What to do with negative anatomical imaging and radioiodine scan?

Details

Serval ID
serval:BIB_75C262DD789C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Detectable thyroglobulin with negative imaging in differentiated thyroid cancer patients. What to do with negative anatomical imaging and radioiodine scan?
Journal
Nuklearmedizin. Nuclear medicine
Author(s)
Giovanella L., Treglia G., Ceriani L., Verburg F.
ISSN
0029-5566 (Print)
ISSN-L
0029-5566
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
53
Number
1
Pages
1-10
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
In the absence of autoantibodies against thyroglobulin (Tg), Tg measurement nowadays is the cornerstone of clinical management of differentiated thyroid cancer patients. DTC patients presenting with a positive Tg measurement without an anatomical correlate on anatomic imaging provide a management challenge to the attending physician. Based on the literature we will provide an overview of the most important steps to undertake in such patients and their potential clinical consequences.

Keywords
Biomarkers/blood, Diagnostic Errors/prevention & control, False Negative Reactions, Humans, Iodine Radioisotopes, Positron-Emission Tomography/methods, Radiopharmaceuticals, Reproducibility of Results, Sensitivity and Specificity, Thyroglobulin/blood, Thyroid Neoplasms/blood, Thyroid Neoplasms/diagnostic imaging, Differentiated thyroid carcinoma, positron emission tomography, thyroglobulin, whole body scan
Pubmed
Web of science
Create date
20/08/2017 19:51
Last modification date
20/08/2019 15:33
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