Vascular mechanisms in the developmental programming of cardio-vascular disease.

Détails

ID Serval
serval:BIB_73534C430BB7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Vascular mechanisms in the developmental programming of cardio-vascular disease.
Périodique
La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
Auteur(s)
Tauzin L., Risso F., Buffat C., Serra G., Simeoni U.
ISSN
0391-5387 (Print)
ISSN-L
0391-5387
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
27
Numéro
5
Pages
18-23
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
Several studies suggest that adverse events during foetal life can program cardiovascular diseases in adulthood. Barker et al. identified a relationship between low birth weight and an increased risk of arterial hypertension, carotid arteriosclerosis, and mortality by coronary heart disease or stroke in adulthood. These findings led to the "foetal origins" hypothesis, which is that cardiovascular disease originates in the adaptations to an adverse intrauterine environment. Such adaptations may permanently alter the cardiovascular structure and physiology through the process of programming. Several factors, such as impaired foetal growth, premature birth or postnatal growth of low birth weight infants may be involved, but to which extent is still unclear.
Mots-clé
Arteries/pathology, Arteries/physiopathology, Cardiovascular Diseases/embryology, Elastin/physiology, Fetal Development, Humans, Infant, Newborn, Infant, Premature
Pubmed
Création de la notice
22/02/2015 12:54
Dernière modification de la notice
03/03/2018 18:19
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