Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis.
European journal of pediatrics
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results.
Acute Disease, Acyclovir, Diagnosis, Differential, Female, Hepatitis, Viral, Human, Herpes Simplex, Humans, Infant, Newborn, Male, Necrosis, Simplexvirus, Time Factors
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