Article: article d'un périodique ou d'un magazine.
Etude de cas (case report): rapporte une observation et la commente brièvement.
End-stage cystic fibrosis: improved diabetes control 2 years after successful isolated pancreatic cell and double-lung transplantation.
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Publication types: Case Reports ; Journal Article ; Review
Over a period of years, insulin-dependent diabetes and respiratory insufficiency developed in a 35-year-old patient with end-stage cystic fibrosis. After waiting more than 4 years while receiving maintenance treatment with continuous liquid O2 and nasal ventilation, the patient underwent double-lung and pancreatic islet cell transplantation. Subsequently, the patient has enjoyed a normal life with full employment and much better control of his diabetes. Pancreatic islet cell transplantation is a simple and innocuous technique easily added to the end of lung transplantation. These new pancreatic cells, although locally injected, are still secreting more than 2 years later as assessed by repeated C-peptide measurements.
Acute Disease, Adult, Combined Modality Therapy, Cystic Fibrosis/surgery, Diabetes Mellitus, Type 1/surgery, Follow-Up Studies, Humans, Islets of Langerhans Transplantation, Lung Transplantation, Male, Remission Induction, Respiratory Insufficiency/surgery, Time Factors
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